4.2 Review

Application of N-halo reagents in organic synthesis

Journal

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 4, Issue 2, Pages 126-174

Publisher

SPRINGER
DOI: 10.1007/BF03245963

Keywords

N-halo reagents; N-halo imides; N-halo amines; N-halo sulfonamides; N-halo amides; N-halo sulfonimides

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This review article summarizes published data on the application of N-balo reagents (such as N-halo amines, N-halo amides and/or imides, N-halo sulfonamides and/or imides, and etc.) in various organic functional group transformations such as: oxidation reactions, deprotection and protection of different functional groups, halogenation of saturated and unsaturated compounds, acylation of alcohols, phenols, amines or thiols, epoxidation of alkenes, aziridination and etc. The main purpose of writing this review is encouraging of active researchers interested to this field for the synthesis of new N-halo reagents specially with different halogens and applications of these new N-halo reagents in organic reactions or finding more and more applications of existing N-halo reagents in organic synthesis.

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