Journal
JOURNAL OF PERIODONTOLOGY
Volume 78, Issue 6, Pages 1164-1175Publisher
AMER ACAD PERIODONTOLOGY
DOI: 10.1902/jop.2007.060422
Keywords
conjunctivitis; deficiency; periodontitis; plasminogen; treatment
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Background: Hypoplasminogenemia is a rare condition that is associated with ligneous conjunctivitis, a form of chronic conjunctivitis characterized by firm, fibrin-rich, pseudomembranous lesions on the tarsal conjunctivae and oral lesions. Pseudomembranes may develop on the gingivae, and there may be periodontal involvement. Methods: Several therapeutic approaches have been developed to treat such patients, but they have had limited effect. We used gingivectomies, topical heparin, and corticosteroids to treat periodontal lesions in an 18-year-old girl. Results: This approach had no benefit. Conclusion: The question remains about how best to manage patients with hypoplasminogenemia.
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