Journal
NEUROCHIRURGIE
Volume 53, Issue 2-3, Pages 131-135Publisher
MASSON EDITEUR
DOI: 10.1016/j.neuchi.2007.02.004
Keywords
cavernomas; cavernous angiomas
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Central nervous system cavernomas are vascular malformations, which occur in two circumstances: sporadic forms and familial autosomal dominant forms. The lesion consists of enlarged, closely packed vessels without interposition of brain parenchyma, surrounded by hemosiderin and gliosis, calcified in few cases. In 80% of sporadic forms the lesion is unique, multiple lesions are rare (median: 4). In familial forms the lesions are always multiple. Cavernomas are often associated with other vascular malformations, especially with venous developmental anomalies. The size of cavernomas is variable from 1 mm to several centimeters. About 70% of cases are supratentorial and 30% in the posterior fossa, particularly in the brain stem. Macroscopic and histopathological findings are typic and the diagnostic is generally easy. (c) 2007 Publie par Elsevier Masson SAS.
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