4.6 Article

Bovine serum albumin-coated quantum dots as a cytoplasmic viscosity probe in a single living cell

Journal

ANALYTICAL METHODS
Volume 4, Issue 7, Pages 1903-1905

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ay25318f

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Funding

  1. Ministry of Education, Science, Sport, and Culture of Japan [19550157, 2/22/006]
  2. Grants-in-Aid for Scientific Research [21221006, 24790036, 19550157] Funding Source: KAKEN

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We report that bovine serum albumin (BSA)-coated quantum dots can be used as a fluorescent probe for measuring the cytoplasmic viscosity of a single living cell: fluorescence correlation spectroscopy measurements for a HeLa cell incorporating BSA-quantum dots show that the viscosity of cytoplasm is 4.7 times greater than that of water.

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