Journal
ANALYTICAL METHODS
Volume 4, Issue 6, Pages 1498-1506Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1ay05384a
Keywords
-
Ask authors/readers for more resources
We show the use of NMR spectroscopy to develop detailed understanding of a reaction mechanism during development of a manufacturing process for an active pharmaceutical ingredient (API). This includes structural elucidation of reaction starting materials, intermediates and products. The method is able to generate an immediate mass balance through quantitative profiling of all materials involved in the reaction. A straightforward reaction monitoring methodology was employed using existing laboratory based equipment.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available