4.1 Article

Repair of spinal cord injury by transplantation of olfactory ensheathing cells

Journal

COMPTES RENDUS BIOLOGIES
Volume 330, Issue 6-7, Pages 557-560

Publisher

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.crvi.2007.03.010

Keywords

adult; CNS; axotomy; regeneration; paraplegia; stem cells

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Repair of spinal cord injury requires that severed axons are able to regenerate. Regrowth of axons is impeded by the loss of astrocytic pathways caused at the time of injury. Ensheathing glial cells cultured from the adult olfactory system can be transplanted into lesions and mediate both regeneration of axons and recovery of function.

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