Journal
IMMUNOLOGY AND CELL BIOLOGY
Volume 85, Issue 4, Pages 274-279Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.icb.7100053
Keywords
cytotoxic T cell; estimation of killing rates; mathematical modeling
Categories
Ask authors/readers for more resources
By killing infected host cells, cytotoxic T lymphocytes (CTL) mediate an important defense mechanism against viruses and other intracellular pathogens. Quantitative aspects of this killing process have been studied for several decades in vitro. More recently, methods have been developed to measure the timescales of CTL killing in vivo. Here, we review the estimates of kinetic rates involved in CTL killing which were obtained in these studies, and elaborate on the differences between them.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available