Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 71, Issue 6, Pages 1595-1597Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.70100
Keywords
S-adenosylmethionine; S-adenosylmethionine (SAM); Saccharomyces cerevisiae
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S-adenosylmethionine (SAM) accumulated in cultured yeast cells and affected growth in two ways. High levels of intracellular SAM in yeast inhibited early growth, but increased growth in medium without sources of nitrogen and sulfur. Accumulated SAM in the yeast cells was recycled as a nutritional source depending on the sulfur and nitrogen contents of the medium.
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