Journal
ANALYTICAL LETTERS
Volume 42, Issue 18, Pages 2951-2961Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00032710903202006
Keywords
HPLC; ibuprofen; pharmaceutical tablets; pseudoephedrine hydrochloride; validation
Categories
Funding
- A. Allioui, C. Simon, and S. Mouyen
Ask authors/readers for more resources
An isocratic HPLC method was developed and validated for the simultaneous determination of ibuprofen (IBU) and pseudoephedrine hydrochloride (PSE). Chromatography was carried out on an Apex phenyl column using 0.025M acetic acid, triethylamine solution (pH 4.5) - acetonitrile (80:20, v/v) as mobile phase at a flow rate of 1mL center dot min-1. UV detection was performed at a wavelength of 210nm. The method was validated for specificity, linearity, accuracy, precision, and was successfully applied to pharmaceutical tablets of Rhinadvil (R).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available