Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 16, Issue 3, Pages 5510-5516Publisher
MDPI AG
DOI: 10.3390/ijms16035510
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Funding
- Young Scientist Grant-Regione Emilia Romagna-Alessandro Liberati
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The aim of this research was to determine the levels of human leukocyte antigen G (HLA-G) and endometrial Natural Killer ((e)NK) cell percentages in uterine flushing samples from primary and secondary infertile women. sHLA-G levels were lower in the uterine flushing samples from primary infertile women in comparison with women with secondary infertility. Lower CD56(+)KIR2DL4(+) (e)NK cell percentages were detected in primary infertile women compared with secondary infertile women. This is the first study demonstrating that primary and secondary unexplained infertilities are characterized by different basal sHLA-G levels and CD56(+)KIR2DL4(+) (e)NK cell percentages.
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