4.7 Article

Staphylococcus aureus strains that are hypersusceptible to resistance gene transfer from enterococci

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 51, Issue 6, Pages 2189-2191

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01442-06

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Funding

  1. Wellcome Trust Funding Source: Medline

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We identified naturally occurring Staphylococcus aureus mutants of the restriction modification pathway Saul, including bovine lineage ST151. In a model of vancomycin resistance transfer from Enterococcus faecalis, ST151 isolates are 500 times more susceptible than human S. aureus isolates. The eradication of hyper-recipient strains may reduce the evolution of vancomycin-resistant S. aureus.

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