Journal
EXPERIMENTAL CELL RESEARCH
Volume 313, Issue 10, Pages 2157-2166Publisher
ELSEVIER INC
DOI: 10.1016/j.yexcr.2007.03.004
Keywords
nuclear envelope; nuclear lamina; cell cycle; lamina associated protein
Categories
Ask authors/readers for more resources
Lamins are the main component of the nuclear lamina and considered to be the ancestors of all intermediate filament proteins. They are localized mainly at the nuclear periphery where they form protein complexes with integral proteins of the nuclear inner membrane, transcriptional regulators, histories and chromatin modifiers. Studying lamins in invertebrate species has unique advantages including the smaller number of lamin genes in the invertebrate genomes and powerful genetic analyses in Caenorkabditis elegans and Drosophila melanogaster. These simpler nuclear lamina systems allow direct analyses of their structure and functions. Here we give an overview of recent advances in the field of invertebrate nuclear lamins with special emphasis on their evolution, assembly and functions. (c) 2007 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available