Journal
ANALYTICAL CHEMISTRY
Volume 86, Issue 5, Pages 2289-2296Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ac404236y
Keywords
-
Categories
Funding
- 973 Program [2011CB935800, 2013CB933700]
- NSF of China [21275149, 21205124, 21321003]
Ask authors/readers for more resources
A simple and effective strategy for designing ratiometric fluorescent nanosensor has been described in this work. A carbon dots (CDs) based dual-emission nanosensor for Cu2+ detection was prepared by coating CDs on the surface of Rhodamine B-doped silica nanoparticles. The fluorescent CDs were synthesized using N-(beta-aminoethyl)-gamma-aminopropyl methyldimethoxysilane (AEAPMS) as the main raw material, so that the residual ethylenediamine groups and methoxysilane groups on the surface of CDs can serve as the Cu2+ recognition sites and the silylation reaction groups. The obtained nanosensor showed characteristic fluorescence emissions of Rhodamine B (red) and CDs (blue) under a single excitation wavelength. Upon binding to Cu2+, only the fluorescence of CDs was quenched, resulting in the ratiometric fluorescence response of the dual-emission silica nanoparticles. This ratiometric nanosensor exhibited good selectivity to Cu2+ over other substances, such as metal ions, amino acids, proteins, and vitamin C. The ratio of F-467/F-585 linearly decreased with the increasing of Cu2+ concentration in the range of 0 to 3 x 10(-6) M, a detection limit as low as 35.2 nM was achieved. Additionally, this nanosensor was successfully applied for the ratiometric fluorescence imaging of Cu2+ in cells and determination of Cu2+ in real tap water.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available