Journal
CLINICAL CANCER RESEARCH
Volume 13, Issue 12, Pages 3449-3459Publisher
AMER ASSOC CANCER RESEARCH
DOI: 10.1158/1078-0432.CCR-07-0238
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Funding
- MRC [G0601746] Funding Source: UKRI
- Medical Research Council [G0601746] Funding Source: researchfish
- Medical Research Council [G0902173, G0601746] Funding Source: Medline
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This article reviews the application of dynamic contrast-enhanced magnetic resonance imaging in both clinical studies and early-phase trials of angiogenesis inhibitors. Emphasis is placed on how variation in image acquisition and analysis affects the meaning and use of derived variables. We then review the potential for future developments, with particular reference to the application of dynamic contrast-enhanced magnetic resonance imaging to evaluate the heterogeneity of tumor tissues.
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