Journal
ANALYTICAL CHEMISTRY
Volume 86, Issue 12, Pages 5638-5641Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ac5014805
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Funding
- National Research Foundation (NRF) - Korean Government [2011-0028663]
- Priority Research Centers Program through the NRF [2009-0093826]
- National Research Foundation of Korea [2011-0028663] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Mitochondria trafficking plays an essential role for supplying energy in the neuronal system. We report here a red emissive two-photon probe for mitochondria (CMT-red) that showed high selectivity and robust staining ability for mitochondria, high photostability under a two-photon microscopy imaging condition, and low cytotoxicity. This probe can be easily loaded into live cells and tissue and used for real-time, high resolution imaging of the mitochondria trafficking in primary cortical neurons as well as in rat hippocampal tissue.
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