Journal
OPTICS LETTERS
Volume 32, Issue 12, Pages 1674-1676Publisher
OPTICAL SOC AMER
DOI: 10.1364/OL.32.001674
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Funding
- NCI NIH HHS [R33 CA109988, U54 CA105296] Funding Source: Medline
- NIDDK NIH HHS [K08 DK067618-04, K08 DK067618, K08 DK067618-05, DK067618] Funding Source: Medline
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We perform Monte Carlo simulations to show that the dual-axes (DA) confocal architecture has superior rejection of multiply scattered photons in tissue to that of single axis. As a result, the DA configuration provides improved signal-to-noise ratio and dynamic range, and thus is sensitive to ballistic photons from deeper within tissue, features that are particularly useful for performing vertical cross-sectional reflectance images in tissue. (C) 2007 Optical Society of America
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