Journal
ANALYTICAL CHEMISTRY
Volume 86, Issue 11, Pages 5323-5329Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ac5001338
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [21275001]
- Natural Science Foundation of Anhui Province [1208085QB20]
Ask authors/readers for more resources
In this paper, we have presented a novel strategy to fabricate fluorescent boronic acid modified carbon dots (C-dots) for nonenzymatic blood glucose sensing applications. The functionalized C-dots are obtained by one-step hydrothermal carbonization, using phenylboronic acid as the sole precursor. Compared with conventional two-step fabrication of nanoparticle-based sensors, the present synthesis-modification integration strategy is simpler and more efficient. The added glucose selectively leads to the assembly and fluorescence quenching of the C-dots. Such fluorescence responses can be used for well quantifying glucose in the range of 9-900 mu M, which is 10-250 times more sensitive than that of previous boronic acid based fluorescent nanosensing systems. Due to inert surface, the C-dots can well resist the interferences from various biomolecules and exhibit excellent selectivity. The proposed sensing system has been successfully used for the assay of glucose in human serum. Due to simplicity and effectivity, it exhibits great promise as a practical platform for blood glucose sensing.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available