Journal
ORGANIC LETTERS
Volume 9, Issue 13, Pages 2441-2444Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol070749f
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Funding
- NCI NIH HHS [CA-109164] Funding Source: Medline
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A palladium-catalyzed aromatic decarboxylation reaction has been developed. With electron-rich aromatic acids, the reaction proceeds efficiently under fairly mild conditions in good yields. The method was useful with complex functionalized substrates containing hindered carboxylic acids.
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