4.8 Article

Boolean Logic Tree of Graphene-Based Chemical System for Molecular Computation and Intelligent Molecular Search Query

Journal

ANALYTICAL CHEMISTRY
Volume 86, Issue 9, Pages 4494-4500

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ac5004008

Keywords

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Funding

  1. National Natural Science Foundation of China [20975083, 21273174]
  2. Municipal Science Foundation of Chongqing City [CSTC2013jjB00002]
  3. Fundamental Research Funds for the Central Universities [XDJK2013D006]
  4. Innovation and Technology Foundation of Southwest University for Excellent Doctoral Student [kb2011010]

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The most serious, and yet unsolved, problem of constructing molecular computing devices consists in connecting all of these molecular events into a usable device. This report demonstrates the use of Boolean logic tree for analyzing the chemical event network based on graphene, organic dye, thrombin aptamer, and Fenton reaction, organizing and connecting these basic chemical events. And this chemical event network can be utilized to implement fluorescent combinatorial logic (including basic logic gates and complex integrated logic circuits) and fuzzy logic computing. On the basis of the Boolean logic tree analysis and logic computing, these basic chemical events can be considered as programmable words and chemical interactions as syntax logic rules to construct molecular search engine for performing intelligent molecular search query. Our approach is helpful in developing the advanced logic program based on molecules for application in biosensing nanotechnology, and drug delivery.

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