Journal
OPTICS EXPRESS
Volume 15, Issue 13, Pages 8115-8124Publisher
OPTICAL SOC AMER
DOI: 10.1364/OE.15.008115
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We report on cross-sectional imaging of dynamic biological specimens using a spectral domain phase microscopy (SDPM) system capable of operating at a line rate of 19 kHz. This system combines the time-sensitive capabilities of SDPM with the multi-point acquisition features of related phase-sensitive techniques. The presented phase portraits and B-scan phase images of spontaneously beating embryonic cardiomyocytes and cytoplasmic flow in A. proteus offer insight into the nature and timing of the observed cellular phenomena, demonstrating the utility of this technique for dynamic cell studies. (C) 2007 Optical Society of America
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