Journal
ANALYTICAL CHEMISTRY
Volume 83, Issue 17, Pages 6778-6784Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ac201462d
Keywords
-
Categories
Funding
- 863 Project [2010AA06Z302]
- NSFC [20903 100]
- National Basic Research Program of China [2011CB935800]
Ask authors/readers for more resources
Magnetic Fe3O4 particle aggregates were prepared by cross-linking Fe3O4 nanoparticles bearing surface carbonyl groups with poly-L-lysine. Upon further coupling with antiparaoxon methyl polyclonal antibody, the resultant particle aggregate-based probes were used in a lateral flow immunochromatographic assay (LFIA) of pesticide residue of paraoxon methyl. The results were compared with that achieved by using the mother Fe3O4 nanoparticles. More quantitative results on the signal amplification effect endowed by the controlled aggregation of Fe3O4 nanoparticles were extracted by relative optical density analysis. Under optimized conditions, a detection limit of 1.7 ng/mL for paraoxon methyl was achieved by using the particle aggregates, which is almost 40-fold lower than that based on the mother Fe3O4 nanoparticles.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available