Journal
ANALYTICAL CHEMISTRY
Volume 79, Issue 13, Pages 5087-5092Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ac0702903
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Funding
- National Research Foundation of Korea [핵06A1107] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Microparticles or biological cells mixed in water were separated using the combination of an electrical force due to dielectrophoresis and a mechanical one generated in an evaporating droplet. Micropatterned electrodes of Au were fabricated on the silicon dioxide layer and were used to generate dielectrophoresis. Polystyrene particles, red blood cells. and E. coli were used as separating objects. Microparticles and biological cells were separated by adjusting the amplitude and frequency of the applied voltage. Although the mechanical force was enough to transport the particles to the boundary of the droplet, nevertheless, it could not detach the particles trapped at the electrode. Based on this work, the microparticles and biological cells can be separated, controlled, and sensed without using a liquid pumping unit.
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