4.4 Review

The Wnt signaling pathway and bone metabolism

Journal

CURRENT OPINION IN RHEUMATOLOGY
Volume 19, Issue 4, Pages 376-382

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/BOR.0b013e32816e06f9

Keywords

beta-catenin; arthritis; low-density lipoprotein receptor related protein 5; sclerostin; Wnt

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Understanding the role that the Writ signaling pathways play in the regulation of bone metabolism offers great promise for the developmental of new paradigms and pharmaceutical strategies for the treatment of various 1 diseases such as osteoporosis, rheumatoid arthritis and osteoarthritis. Progress in this regard has already been made.

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