Type A eagerness-energy across developmental periods predicts adulthood carotid intima-media thickness -: The cardiovascular risk in young Finns study

Objective - We examined the Type A behavior across developmental periods as a predictor of adult carotid artery intima- media thickness ( IMT). Methods and Results - In this prospective cohort study of 408 men and 606 women, socioeconomic background and biological risk factors of participants were assessed at baseline at age 6 to 18 years of age, Type A behavior ( Hunter- Wolf A- B Rating Scale) at the 6-, 9-, and 21- year follow- ups ( subjects being 12 to 24, 15 to 27, and 27 to 39 years, respectively), and carotid IMT, adulthood socioeconomic situation, and biological risk factors at the 21- year follow- up when participants were at age 27 to 39 years of age. In men, the eagerness- energy component of Type A behavior, measured at any time point, was associated with thicker carotid IMT ( P < 0.008, P < 0.04, P < 0.03, and P < 0.02 for the first, second, and third assessment, and for the average score, respectively), and this association was independent of early and adult risk factors. In women, the hard- driving component at baseline ( P < 0.04) but not later was independently related to thinner carotid IMT. The other components of Type A behavior ( impatience- aggression and leadership) were not associated with IMT. Conclusions - Eagerness- energy component of Type A behavior over different developmental transitions seems to be a robust predictor of IMT in men.