4.8 Article

Online-Calibration for Reliable and Robust Lab-on-a-Chip Surface Enhanced Raman Spectroscopy Measurement in a Liquid/Liquid Segmented Flow

Journal

ANALYTICAL CHEMISTRY
Volume 83, Issue 21, Pages 8337-8340

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ac2015799

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Funding

  1. Free State of Thuringia
  2. European Union (EFRE) [2008FE9112]

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Concerning the usability of lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS) for analytical tasks applying chemometric data evalutation, a secure, reproducible, and stable data output independent of inconsistent ambient conditions has to be accomplished. In this contribution, we present a new approach to achieve reliable and robust measurements based on segmented flow LOC-SERS via online-wavenumber calibration.

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