Journal
CLINICAL BIOCHEMISTRY
Volume 40, Issue 11, Pages 798-801Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.clinbiochem.2007.03.009
Keywords
betaine; vascular diseases; dietary supplements; water-electrolyte balance; homocysteine
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Objectives: Does abnormal betaine excretion persist? Design and methods: Patients (10) with abnormal excretion in 1998 were recalled in 2005. Subsequent urine samples were collected on 4 days from persistently abnormal subjects. Results: Half the 1998 abnormal patients were abnormal in 2005. Only 1/20 controls was abnormal (p=0.015). All patients with abnormal excretion in 1998 and 2005 had abnormal excretion on successive days while no controls did. Conclusions: High betaine excretion may be chronic and a health risk.(c) 2007 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
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