Journal
ANALYTICAL CHEMISTRY
Volume 82, Issue 24, Pages 10246-10250Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ac1027066
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Funding
- Tekes-the Finnish Funding Agency for Technology and Innovation
- UPM-Kymmene Oyj
- BASF Oyj
- Tervakoski Oyj
- Orion Diagnostica Oy
- Hansaprint Oy
- Oy Medix Biochemica Ab
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This Technical Note demonstrates a simple method based on flexographic printing of polystyrene to form liquid guiding boundaries and layers on paper substrates. The method allows formation of hydrophobic barrier structures that partially or completely penetrate through the substrate. This unique property enables one to form very thin fluidic channels on paper, leading to reduced sample volumes required in point-of-care diagnostic devices. The described method is compatible with roll-to-roll flexography units found in many printing houses, making it an ideal method for large-scale production of paper-based fluidic structures.
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