Photoelectrochemical detection of pentachlorophenol with a Multiple Hybrid CdSexTe1-x/TiO2 Nanotube Structure-Based Label-Free Immunosensor

Driven by the urgent demand of detecting trace amounts of pentachlorophenol (PCP) in contaminative water, a label-free immunosensor with ultra sensitivity and high selectivity was constructed based on a hybrid CdSexTe1-x. (0 x 1) nanocrystal (NCs)-modified TiO2 nanotube (NT) arrays for the first time The CdSexTe1-x NCs were photoelectrodeposited on inner and outer space of the TiO2 NTs, leading to high photoelectrical conversion efficiency in the visible region PCP antibodies are covalently conjugated on the TiO2 NTs due to the large surface area and good biocompatibility Since the photocurrent is highly dependent on the TiO2 surface properties, the specific interaction between PCP and the antibodies results in a sensitive change in the photocurrent, with a limit of detection (LOD) of 1 pM High sensor-to-sensor reproducibility is achieved The sensor was applied for the direct analysis of river water samples