Related references
Note: Only part of the references are listed.Efficacy and safety of delayed-release dimethyl fumarate in patients newly diagnosed with relapsing-remitting multiple sclerosis (RRMS)
Ralf Gold et al.
MULTIPLE SCLEROSIS JOURNAL (2015)
The MEK/ERK pathway is the primary conduit for Borrelia burgdorferi-induced inflammation and P53-mediated apoptosis in oligodendrocytes
Geetha Parthasarathy et al.
APOPTOSIS (2014)
Anti-oxidizing effect of the dichloromethane and hexane fractions from Orostachys japonicus in LPS-stimulated RAW 264.7 cells via upregulation of Nrf2 expression and activation of MAPK signaling pathway
Hyeong-Seon Lee et al.
BMB REPORTS (2014)
MDA-7/IL-24 inhibits Nrf2-mediated antioxidant response through activation of p38 pathway and inhibition of ERK pathway involved in cancer cell apoptosis
H. Tian et al.
CANCER GENE THERAPY (2014)
5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19
Qin Wang et al.
CELLULAR SIGNALLING (2014)
Effects of Delayed-Release Dimethyl Fumarate (DMF) on Health-Related Quality of Life in Patients With Relapsing-Remitting Multiple Sclerosis: An Integrated Analysis of the Phase 3 DEFINE and CONFIRM Studies
Mariko Kita et al.
CLINICAL THERAPEUTICS (2014)
Multiple Sclerosis: Current Knowledge and Future Outlook
Christian P. Kamm et al.
EUROPEAN NEUROLOGY (2014)
Rapid Identification of Keap1-Nrf2 Small-Molecule Inhibitors through Structure-Based Virtual Screening and Hit-Based Substructure Search
Chunlin Zhuang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Discovery of Potent Keap1-Nrf2 Protein-Protein Interaction Inhibitor Based on Molecular Binding Determinants Analysis
Zheng-Yu Jiang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Effects of delayed-release dimethyl fumarate on MRI measures in the Phase 3 DEFINE study
Douglas L. Arnold et al.
JOURNAL OF NEUROLOGY (2014)
Nrf2 Regulates Neurogenesis and Protects Neural Progenitor Cells Against Aβ Toxicity
Virve Karkkainen et al.
STEM CELLS (2014)
The Predicted Molecular Weight of Nrf2: It Is What It Is Not
Alexandria Lau et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism
Douglas Marcotte et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction
Longqin Hu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
The fumaric acid ester BG-12: a new option in MS therapy
De-Hyung Lee et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2013)
Thioredoxin-interacting Protein Mediates High Glucose-induced Reactive Oxygen Species Generation by Mitochondria and the NADPH Oxidase, Nox4, in Mesangial Cells
Anu Shah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Sulfiredoxin-1 protects PC12 cells against oxidative stress induced by hydrogen peroxide
Qiong Li et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2013)
The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism
Raja Settivari et al.
NEUROTOXICOLOGY (2013)
BG-12 in Multiple Sclerosis
J. Theodore Phillips et al.
SEMINARS IN NEUROLOGY (2013)
p38MAPK and ERK1/2 dictate cell death/survival response to different pro-oxidant stimuli via p53 and Nrf2 in neuroblastoma cells SH-SY5Y
Giuseppe Filomeni et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Effects of dimethyl fumarate on neuroprotection and immunomodulation
Philipp Albrecht et al.
JOURNAL OF NEUROINFLAMMATION (2012)
c-Jun-dependent sulfiredoxin induction mediates BDNF protection against mitochondrial inhibition in rat cortical neurons
Chia-Lin Wu et al.
NEUROBIOLOGY OF DISEASE (2012)
Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis
Robert J. Fox et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Fumarates Promote Cytoprotection of Central Nervous System Cells against Oxidative Stress via the Nuclear Factor (Erythroid-Derived 2)-Like 2 Pathway
Robert H. Scannevin et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1
Shao Xia Lin et al.
ASN NEURO (2011)
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
Ralf A. Linker et al.
BRAIN (2011)
CCL5 induces a pro-inflammatory profile in microglia in vitro
Jelena Skuljec et al.
CELLULAR IMMUNOLOGY (2011)
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
Keiko Taguchi et al.
GENES TO CELLS (2011)
Opioid-induced Down-Regulation of RGS4 ROLE OF UBIQUITINATION AND IMPLICATIONS FOR RECEPTOR CROSS-TALK
Qin Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Stages of neuronal morphological development in vitro-An automated assay
Michelle K. Leach et al.
JOURNAL OF NEUROSCIENCE METHODS (2011)
Cross-talk between CD4+ T-cells and neural stem/progenitor cells
Julia Knight et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2011)
Efficacy of Fumaric Acid Esters in the R6/2 and YAC128 Models of Huntington's Disease
Gisa Ellrichmann et al.
PLOS ONE (2011)
Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions
Jack van Horssen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes
David Vauzour et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2010)
Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress
Sergei Chuikov et al.
NATURE CELL BIOLOGY (2010)
Effects of Fumaric Acids on Cuprizone Induced Central Nervous System De- and Remyelination in the Mouse
Darius Moharregh-Khiabani et al.
PLOS ONE (2010)
The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease
Marcus J. Calkins et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
The effect of interferon-β on mouse neural progenitor cell survival and differentiation
Marek Hirsch et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Fumaric Acid and its Esters: An Emerging Treatment for Multiple Sclerosis
D. Moharregh-Khiabani et al.
CURRENT NEUROPHARMACOLOGY (2009)
The Nrf2-ARE cytoprotective pathway in astrocytes
Marcelo R. Vargas et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2009)
Cytoprotective Nrf2 Pathway Is Induced In Chronically Txnrd 1-Deficient Hepatocytes
Elena S. Suvorova et al.
PLOS ONE (2009)
Multiple sclerosis: An immune or neurodegenerative disorder?
Bruce D. Trapp et al.
ANNUAL REVIEW OF NEUROSCIENCE (2008)
Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression
J. van Horssen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Neuroprotection and neuroregeneration in multiple sclerosis
Martin Stangel
JOURNAL OF NEUROLOGY (2008)
G-Protein-Coupled Receptor Screen Reveals a Role for Chemokine Receptor CCR5 in Suppressing Microglial Neurotoxicity
Kazushige Gamo et al.
JOURNAL OF NEUROSCIENCE (2008)
Immunomodulation by neural stem cells
Tamir Ben-Hur
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
The therapeutic plasticity of neural stem/precursor cells in multiple sclerosis
Stefano Pluchino et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)
Network Inference Algorithms Elucidate Nrf2 Regulation of Mouse Lung Oxidative Stress
Ronald C. Taylor et al.
PLOS COMPUTATIONAL BIOLOGY (2008)
Chemokines and chemokine receptors in multiple sclerosis. Potential targets for new therapies
Adam Szczucinski et al.
ACTA NEUROLOGICA SCANDINAVICA (2007)
MAPK phosphatases - regulating the immune response
Yusen Liu et al.
NATURE REVIEWS IMMUNOLOGY (2007)
NF-κB functions in the nervous system:: From development to disease
Sylvie Memet
BIOCHEMICAL PHARMACOLOGY (2006)
The neurobiology of multiple sclerosis: Genes, inflammation, and neurodegeneration
Stephen L. Hauser et al.
NEURON (2006)
Determinants of CCL5-driven mononuclear cell migration across the blood-brain barrier. Implications for therapeutically modulating neuroinflammation
Eroboghene E. Ubogu et al.
JOURNAL OF NEUROIMMUNOLOGY (2006)
Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration
S. Schilling et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2006)
The therapeutic potential of neural stem cells
G Martino et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Immunological patterns identifying disease course and evolution in multiple sclerosis patients
R Furlan et al.
JOURNAL OF NEUROIMMUNOLOGY (2005)
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
AD Kraft et al.
JOURNAL OF NEUROSCIENCE (2004)
Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression
DA Bloom et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Neural stem cells - An overview
R Galli et al.
CIRCULATION RESEARCH (2003)
U0126 and PD98059, specific inhibitors of MEK, accelerate differentiation of RAW264.7 cells into osteoclast-like cells
H Hotokezaka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
New concepts in the immunopathogenesis of multiple sclerosis
B Hemmer et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Prevalence estimates for MS in the United States and evidence of an increasing trend for women
CW Noonan et al.
NEUROLOGY (2002)
Absence of mitochondrial superoxide dismutase results in a murine hemolytic anemia responsive to therapy with a catalytic antioxidant
JS Friedman et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
G Pearson et al.
ENDOCRINE REVIEWS (2001)
Share Paper
