Journal
EMERGING INFECTIOUS DISEASES
Volume 13, Issue 7, Pages 1101-1104Publisher
CENTER DISEASE CONTROL
DOI: 10.3201/eid1307.070227
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- Wellcome Trust Funding Source: Medline
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In 50 healthy Peruvian shantytown residents, zinc cream applied to tuberculosis skin-test sites caused a 32% increase in induration compared with placebo cream. Persons with lower plasma zinc had smaller skin-test reactions and greater augmentation with zinc cream. Zinc deficiency caused false-negative skin-test results, and topical zinc supplementation augmented anti mycobacterial immune responses enough to improve diagnosis.
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