Journal
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 7, Issue 7, Pages 997-1007Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1517/14712598.7.7.997
Keywords
cancer; immunotherapy; vaccine; virus; virus-like particles
Ask authors/readers for more resources
Virus-like particles (VLPs) are self-assembling, non-replicating particles lacking the viral genome that are formed by one or several viral structural proteins. VLPs can be purified after expression in yeast cells, insect cells using baculoviruses, Escherichia coli or mammalian cells. Recently, vaccines based on VLPs have come into focus with the FDA approval of a VLP-based vaccine against human papilloma viruses. However, this application of VLPs is just one of many developments within the VLP field. Other potential applications under development besides vaccines against viruses or cancers also include gene delivery and treatment of different disorders.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available