Space-time analysis of the dengue spreading dynamics in the 2004 Tartagal outbreak, Northern Argentina

The spreading dynamic of the 2004 dengue fever outbreak that occurred in Tartagal, Northwestern Argentina, was investigated. 9 A total of 487 suspected dengue cases were recorded and geo-referenced. Maps of daily cases were generated for the 109 days of the outbreak. The epidemic affected the majority of the city within I I days. The age-distribution of the cases was different from the population age-distribution. The spatio-temporal clustering of the cases was analyzed using Knox test concept. Results of the space and time geo-referencing of the cases showed outbreak spotlights and spreading patterns that could be related to entomologic and epidemiologic factors. An environmental risk prediction model was developed based on a synthetic multi-band image created from LandSat 5 TM satellite image. The potential and limitations of remote sensing data and spatial statistics as landscape epidemiology tools for a dengue surveillance strategy and prevention are discussed. (c) 2007 Elsevier B.V. All rights reserved.