Electrochemical sensing platform based on the highly ordered mesoporous carbon-fullerene system

In this paper, we report a novel all-carbon two-dimensionally ordered nanocomposite electrode system on the basis of the consideration of host-guest chemistry, which utilizes synergistic interactions between a nanostructured matrix of ordered mesoporous carbon (OMC) and an excellent electron acceptor of nanosized fullerene (C-60) to facilitate heterogeneous electron-transfer processes. The integration of OMC-C-60 by covalent interaction, especially its electrochemical applications for electrocatalysis, has not been explored thus far. Such integration may even appear to be counterintuitive because OMC and C-60 provide opposite electrochemical benefits in terms of facilitating heterogeneous electron-transfer processes. Nevertheless, the present work demonstrates the integration of OMC and C-60 can provide a remarkable synergistic augmentation of the current To illuminate the concept, eight kinds of inorganic and organic electroactive compounds were employed to study the electrochemical response at an OMC-C-60 modified glassy carbon (OMC-C-60/GC) electrode for the first time, which shows more favorable electron-transfer kinetics than OMC/GC, carbon nanotube modified GC, C-60/GC, and GC electrodes. Such electrocatalytic behavior at OMC-C-60/GC electrode could be attributed to the unique physicochemical properties of OMC and C-60, especially the unusual host-guest synergy of OMC-C-60, which induced a substantial decrease in the overvoltage for NADH oxidation compared with GC electrode. The ability of OMC-C-60 to promote electron transfer not only suggests a new platform for the development of dehydrogenase-based bioelectrochemical devices but also indicates a potential of OMC-C-60 to be of a wide range of sensing applications because the electrocatalysis of different electroactive compounds at the OMC-C-60/GC electrode in this work should be a good model for constructing a novel and promising electrochemical sensing platform for further electrochemical detection of other biomolecules.