Journal
DERMATOLOGIC CLINICS
Volume 25, Issue 3, Pages 327-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.det.2007.04.011
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This article discusses hypermelanoses present at birth or appearing in the first months of life. They may be transient or permanent, localized-as in cafe-au-lait spots-or segmental, or more rarely, complex or generalized. In most pigmentary diseases, physical examination, including Woods lamp examination and a detailed history, is usually sufficient. Time of onset, distribution pattern, and associated clinical and sometimes histopathologic findings are helpful in differentiating these disorders. Recently, molecular diagnosis has become available for some rare entities, such as hereditary symmetrical dyschromatoses, but the bulk of nevoid lesions are not understood at the molecular level.
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