Journal
JOURNAL OF CYSTIC FIBROSIS
Volume 6, Issue 4, Pages 304-308Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jcf.2006.12.001
Keywords
CFTR; NF-kappa B; pro-inflammatory cytokines
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In cystic fibrosis patients, inflammation is often considered to be secondary to chronic infections. In the present study, we show increased levels of pro-inflammatory proteins in the lungs of a cystic fibrosis foetus compared to the lungs of two normal foetuses. Our findings suggest therefore the existence of an early intrinsic pro-inflammatory state in cystic fibrosis airways. (C) 2006 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.
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