4.6 Article

Two new coumarin glucosides from the roots of Angelica apaensis and their anti-platelet aggregation activity

Journal

ARCHIVES OF PHARMACAL RESEARCH
Volume 30, Issue 7, Pages 799-802

Publisher

PHARMACEUTICAL SOC KOREA
DOI: 10.1007/BF02978827

Keywords

anti-platelet aggregation; 11-O-beta-D-glucopyranosyl thamnosmonin; 12-O-beta-D-glucopyranosyl gosferol; coumarin; Angelica apaensis; Umbelliferae

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Two new coumarin glucosides, 11-O-beta-D-glucopyranosyl thamnosmonin (1) and 12-O-beta-D-glucopyranosyl gosferol (2), were isolated from the roots of Angelica apaensis. Their structures were elucidated spectroscopically. Both compounds showed weak inhibitory effects on rabbit platelet aggregation induced by PAF, AA and APD.

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