4.8 Article

ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry

Journal

NUCLEIC ACIDS RESEARCH
Volume 35, Issue -, Pages W701-W706

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkm371

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Funding

  1. NIDA NIH HHS [P30 DA018310, P30 DA 018310-039002] Funding Source: Medline
  2. NIGMS NIH HHS [GM 067193, R01 GM067193] Funding Source: Medline

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ProSight PTM 2.0 (http://prosightptm2.scs.uiuc.edu) is the next generation of the ProSight PTM web-based system for the identification and characterization of proteins using top down tandem mass spectrometry. It introduces an entirely new data-driven interface, integrated Sequence Gazer for protein characterization, support for fixed modifications, terminal modifications and improved support for multiple precursor ions (multiplexing). Furthermore, it supports data import and export for local analysis and collaboration.

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