Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 129, Issue 27, Pages 8400-+Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ja070238o
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Funding
- NIGMS NIH HHS [R37 GM058867, R01 GM058867, R01 GM058867-11, GM058867] Funding Source: Medline
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The visualization of biomolecules as they function in living systems is important for understanding complex biological processes. Here, we applied the bioorthogonal chemical reporter technique to image cell surface glycans using multiple metabolic labels. We introduced two different chemical reporters into sialic acid and N-acetylgalactosamine (GalNAc) residues and then simultaneously imaged their associated cell surface glycans with fluorescent probes.
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