Journal
MOVEMENT DISORDERS
Volume 22, Issue 9, Pages 1346-1350Publisher
WILEY
DOI: 10.1002/mds.21398
Keywords
Tourette's syndrome; deep brain stimulation; midline thalamic nuclei
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A 48-year-old man with severe, lifelong Tourette's syndrome (TS) characterized by forceful self-injurious motor tics and, obsessive-compulsive disorder was treated with bilateral deep brain stimulation (DBS). The decision to treat was based on his progressive neurological impairment (left sided weakness secondary to spinal cord injury) because of his relentless, violent head jerks. Electrodes were implanted at the level of the medial part of the thalamus (centromedian nucleus, the substantia periventricularis, and the nucleus ventro-oralis interims). DBS resulted in a substantial reduction of tics. These data show that bilateral DBS of the thalamus can have a good effect on severe ties in adult patients suffering from intractable TS. (c) 2007 Movement Disorder Society
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