4.5 Article

ERβ ligands.: Part 6:: 6H-chromeno[4,3-b]quinolines as a new series of estrogen receptor β-selective ligands

Journal

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 17, Issue 14, Pages 4053-4056

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2007.04.068

Keywords

estrogen receptor beta ligands; chromenoquinoline

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A new class of estrogen receptor beta (ERP) ligands based on the 6H-chromeno[4,3-b]quinoline scaffold has been prepared. Several C7-substituted analogues displayed high affinity and modest selectivity for ERP. (C) 2007 Elsevier Ltd. All rights reserved.

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