Journal
ADVANCED MATERIALS
Volume 19, Issue 14, Pages 1874-+Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.200602326
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A high-performance magnetic resonance imaging T-2 contrast agent has been prepared via phase transfer of hydrophobic superparamagnetic iron oxide nanoparticles (SPIONs) to an aqueous solution by using Pluronic F127 copolymers. As seen in the figure, a hierarchical structure of the surface coating is formed and proven to be a crucial characteristic to enhance not only water dispersibility, but also the efficacy as a T-2 contrast agent.
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