4.8 Article

Diarylprolinol silyl ether as catalyst of an exo-selective, enantioselective Diels-Alder reaction

Journal

ORGANIC LETTERS
Volume 9, Issue 15, Pages 2859-2862

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol071009+

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In combined use with CF3CO2H, 2-[bis(3,5-bis-trifluoromethylphenyl) triethylsiloxymethyl]pyrrolidine was found to be an effective organocatalyst of an exo-selective, enantioselective Diels-Alder reaction of alpha,beta-unsaturated aldehydes.

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