4.7 Article

Porous Co3O4 nanosheets as a high-performance non-enzymatic sensor for glucose detection

Journal

ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 410, Issue 29, Pages 7663-7670

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00216-018-1380-4

Keywords

Co3O4 nanosheets; Non-enzymatic sensor; Glucose; High sensitivity

Funding

  1. National Natural Science Foundation of China [51602179, 21333006, 21573135, 11374190, 21675104]
  2. National Basic Research Program of China (973 Program) [2013CB632401]
  3. Recruitment Program for Young Professionals
  4. China and Taishan Scholar Foundation of Shandong Province, China

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Novel porous Co3O4 nanosheets (NSs) were synthesized on the flexible carbon cloth (CC) substrate by a facile hydrothermal method and applied to construct a non-enzymatic sensor for glucose detection. The sensor is based on the electro-catalytic oxidation of glucose on the surface of Co3O4 NSs. Since this particular nanostructure can provide large surface area and more active sites, the Co3O4 NSs non-enzymatic sensor exhibits excellent analytical performance, such as a high sensitivity (8506AmM(-1)cm(-2)), a fast response time (less than 6s), low detection limit of 1M, good selectivity, and long-term stability. The results suggest that the porous Co3O4 NSs have great potential applications in the development of sensors for enzyme-free detection of glucose.

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