Journal
PHYSIOLOGY
Volume 22, Issue -, Pages 261-268Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00017.2007
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Funding
- NHLBI NIH HHS [R01 HL48093] Funding Source: Medline
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Mitochondria have a low affinity for Ca2+, but they take up these ions during normal cell activity because they are in close proximity to the sites of calcium entry into the cell and of internal Ca2+ release. This gives mitochondria privileged access to cytoplasmic Ca2+ without requiring a direct communication with the endoplasmic reticulum.
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