Journal
BRAIN AND LANGUAGE
Volume 102, Issue 2, Pages 165-175Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.bandl.2006.04.016
Keywords
magnetic resonance imaging; perfusion-weighted; stroke; aphasia
Funding
- NIDCD NIH HHS [R01 DC005375, R01 DC005375-07, R01 DC005375-09, R01 DC05375] Funding Source: Medline
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This paper provides a brief review of various uses of magnetic resonance perfusion imaging in the investigation of brain/language relationships. The reviewed studies illustrate how perfusion imaging can reveal areas of brain where dysfunction due to low blood flow is associated with specific language deficits, and where restoration of blood flow to improve the tissue function results in recovery of those deficits. This sort of evidence helps to reveal areas of the brain that are essential to a particular language task. Other studies have provided clues regarding the mechanisms of early language recovery, or have shown how perfusion imaging can identify patients with chronic hypoperfusion due to cerebrovascular stenosis in whom the BOLD effect in fMRI may be absent or reduced in areas of neural activation. (c) 2006 Elsevier Inc. All rights reserved.
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