Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 405, Issue 7, Pages 2341-2352Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-012-6649-4
Keywords
Chromatographic fingerprints; Illegal herbal products; Diode-array detection; Evaporative light scattering detection; Mass spectrometry
Ask authors/readers for more resources
The detection of regulated and forbidden herbs in pharmaceutical preparations and nutritional supplements is a growing problem for laboratories charged with the analysis of illegal pharmaceutical preparations and counterfeit medicines. This article presents a feasibility study of the use of chromatographic fingerprints for the detection of plants in pharmaceutical preparations. Fingerprints were developed for three non-regulated common herbal products-Rhamnus purshiana, Passiflora incarnata L. and Crataegus monogyna-and this was done by combining three different types of detection: diode-array detection, evaporative light scattering detection and mass spectrometry. It is shown that these plants could be detected in respective triturations of the dry extracts with lactose and three different herbal matrices as well as in commercial preparations purchased on the open market.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available