Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 404, Issue 4, Pages 1181-1196Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-012-6149-6
Keywords
Biosensor; Enzyme; Aptamers; Phage; Point of care
Funding
- National Science Foundation Emerging Frontiers in Research and Innovation grant [0937997]
- Directorate For Engineering [0937997] Funding Source: National Science Foundation
- Div Of Chem, Bioeng, Env, & Transp Sys
- Directorate For Engineering [1160262] Funding Source: National Science Foundation
- Emerging Frontiers & Multidisciplinary Activities [0937997] Funding Source: National Science Foundation
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The applications of biosensors range from environmental testing and biowarfare agent detection to clinical testing and cell analysis. In recent years, biosensors have become increasingly prevalent in clinical testing and point-of-care testing. This is driven in part by the desire to decrease the cost of health care, to shift some of the analytical tests from centralized facilities to frontline physicians and nurses, and to obtain more precise information more quickly about the health status of a patient. This article gives an overview of recent advances in the field of biosensors, focusing on biosensors based on enzymes, aptamers, antibodies, and phages. In addition, this article attempts to describe efforts to apply these biosensors to clinical testing and cell analysis.
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