Journal
JOURNAL OF NEUROSCIENCE
Volume 27, Issue 31, Pages 8161-8165Publisher
SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.1554-07.2007
Keywords
choice; utility; frontal cortex; executive; reward; striatum
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Funding
- Intramural NIH HHS Funding Source: Medline
- PHS HHS [NIMH 56446] Funding Source: Medline
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Although the involvement in the striatum in the refinement and control of motor movement has long been recognized, recent description of discrete frontal corticobasal ganglia networks in a range of species has focused attention on the role particularly of the dorsal striatum in executive functions. Current evidence suggests that the dorsal striatum contributes directly to decision-making, especially to action selection and initiation, through the integration of sensorimotor, cognitive, and motivational/emotional information within specific corticostriatal circuits involving discrete regions of striatum. We review key evidence from recent studies in rodent, nonhuman primate, and human subjects.
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