Journal
JOURNAL OF NEUROSCIENCE
Volume 27, Issue 31, Pages 8166-8169Publisher
SOC NEUROSCIENCE
DOI: 10.1523/JNEUROSCI.1556-07.2007
Keywords
conditioned; conditioning; human; learning; prefrontal cortex; primate; rat; reward
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Funding
- NIDA NIH HHS [R01 DA015718-04, R01 DA015718] Funding Source: Medline
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When Pat Goldman-Rakic described the circuitry and function of primate prefrontal cortex in her influential 1987 monograph (Goldman-Rakic, 1987), she included only a few short paragraphs on the orbitofrontal cortex (OFC). That year, there were only nine papers published containing the term orbitofrontal, an average of less than one paper per month. Twenty years later, this rate has increased to 32 papers per month. This explosive growth is partly attributable to the remarkable similarities that exist in structure and function across species. These similarities suggest that OFC function can be usefully modeled in nonhuman and even nonprimate species. Here, we review some of these similarities.
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