Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 397, Issue 3, Pages 991-1007Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-010-3678-8
Keywords
Microfluidics/microfabrication; Immunoassays/ELISA; Biosensors; Bioanalytical methods; Fluid handling/automation multiplex analysis
Funding
- Natural Sciences and Engineering Research Council of Canada
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Immunoassays have greatly benefited from miniaturization in microfluidic systems. This review, which summarizes developments in microfluidics-based immunoassays since 2000, includes four sections, focusing on the configurations of immunoassays that have been implemented in microfluidics, the main fluid handling modalities that have been used for microfluidic immunoassays, multiplexed immunoassays in microfluidic platforms, and the emergence of label-free detection techniques. The field of microfluidic immunoassays is continuously improving and has great promise for the future.
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